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Calaptin (Verapamil)
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Verapamil

Calaptin was given subcutaneously in two doses (1 and 5 mg/kg) to male Wistar rats subjected to adrenal enucleation combined with contralateral adrenalectomy. In addition, the effects of two other calcium channel antagonists, Calaptin and diltiazem, on the MMCs were investigated.

Other names for this medication:
Verapamil, Calan, Calaptin, Isoptin, Verelan,

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Calaptin is used alone or together with other medicines to treat heart rhythm problems, severe chest pain (angina), or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Calaptin is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, Calaptin relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Tablet, Extended Release
  • Capsule, Extended Release

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Secondary mastectomy was performed in three women because the tumour was found to reach the resection margin. Studies on the specificity of cholinesterases in the peripheral nervous system of the rat Nearly forty years ago, at the University of Rome, Giovanni Piancatelli and co-workers discovered the acid-catalyzed water-mediated rearrangement of 2-furylcarbinols into 4-hydroxycyclopentenones. (ii) Soluble IL-13 but not IL-4 or IL-2 blocked the replication of R5111 recombinant virus in J-13R cells. Analysis of two- and three-year trends in antimicrobial resistance in intensive care units using unit-specific antibiograms.

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In a large-animal model of partial SCI treated with implanted AAMs, the authors saw no morphological or histological evidence of axonal regeneration. In a prospective study, these profiles were used to select 6 children (3 predicted responders and 3 predicted nonresponders) who received PRT. In order to better understand the role PR plays in cortical development, we used the cellular-level resolution of immunohistochemistry and in situ hybridization (ISH) to characterize changes in perinatal PR expression within specific cortical lamina.

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Cell fusion would seem to be obviously recognizable upon visual inspection, and many studies employ a simple microscopic fusion index to quantify the rate and extent of fusion in cell culture. Neurotrophins such as nerve growth factor regulate these two cell survival pathways in in vitro studies.

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The potential of Thai indigenous plant species for the phytoremediation of arsenic contaminated land. In addition, significant amounts of complexed MIF (180 kDa under denaturing conditions by Western blot) found in the serum do not bind to the MIF capture antibody. Genetic and pharmacologic antithrombotic interventions were well reflected by CEUS and suggested an important role of the platelet P2Y(12) receptor in early DVT formation.

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Results relating to both prevalence of pressure ulcers (grade I excluded) and the preventive care given to patients at risk or with pressure ulcers accord with those of a larger Dutch study. A cross-sectional descriptive study was conducted from September 2010-January 2011 at selected public health facilities. Our results suggest that nucleotide polymorphisms in regulatory elements of genes encoding controlling factors could be primary targets of natural selection and a driving force behind the evolution of Arabidopsis accessions. We previously showed that systemic administration of 15-deoxy, delta (12, 14) prostaglandin J2 (PGJ2) is neuroprotective in our rodent model of AION (rAION).

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Although diaphragmatic rupture occurs after violent blunt trauma, its diagnosis is often delayed. Trichomegaly of the eyelashes following treatment with cetuximab. Positron emission tomography and functional magnetic resonance imaging studies have already yielded preliminary insights into the neural control of continence mechanisms and their dysfunction. Present findings suggest that classifying a respondent as nondepressed is not sufficient and is still not informative about his or her QOL and attitudes toward aging status.

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Effects of a fire response trait on diversification in replicated radiations. THE ACTIVITY OF GLUTAMINASE I, TRANSAMINASES AND GLUTAMIC ACID AND LACTIC ACID DEHYDROGENASES IN THE DISEASED HUMAN KIDNEY The database application allowed flexible use of the data in novel combinations, and use of a previously published data sets. Determination of carbon dioxide in gaseous samples by gas diffusion-flow injection.

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Nuclear-targeting autoantibodies induced nuclear PARP cleavage accompanied by more pronounced decrease of peripheral white blood cells than Ro/SSA and La/SSB antigen-targeting autoantibodies. For the touch-pressure thresholds, no significant relationship was found between sides at the knee level.

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Cutaneous propionibacteria are implicated in acne pathogenesis, although their exact role in the genesis of inflammation is still poorly understood. In systemic amyloidosis, accumulation of misfolded proteins as extracellular amyloid fibrils in tissues causes severe organ dysfunction, but the molecular events of tissue damage related to amyloid deposition are still largely unknown. Polymerase chain reaction - restriction fragment length polymorphism resulted in the apo-epsilon(2)/epsilon(2) genotype, whereas minisequencing indicated apo-epsilon(2)/epsilon(3).

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Breaking the bad news to the bereaved family needs special skill on the part of the clinicians. Colorectal cancer is the second leading cause of cancer deaths in the United States. It is shown that the type of contrast from the p-n junction can be reversed depending on the position of the contrast aperture restricting the electron beam.

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RNA was extracted from archival lung tissue of 11 patients (mean age, 3.5 days) with CDH. The purpose of this review is to examine our evolving understanding of the pathogenesis of cardiovascular disease in rheumatoid arthritis and to underscore the importance of tailored prevention of cardiovascular disease in this select population. Spatial visual acuity of the falcon, Falco berigora: a behavioural, optical and anatomical investigation. It has a superior toxicity profile to cyclophosphamide and is more effective than azathioprine when used in combination with cyclosporin for renal transplantation. Remarkably, there is an additional level of complexity in cluster number and gene content.

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Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden. The present study aimed to estimate whether sleep disturbances in adolescence predicted sleep disturbances in later years. In the first half of the 20th century, nearly all osteopathic physicians used osteopathic manipulative medicine (OMM) in the care of hospitalized patients. Formation of reactive oxygen species in whole blood was determined by luminol-enhanced CL.

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This procedure allows the simultaneous determination of cited ions in natural, tap and waste waters good reliability of the determination was proved. Among the diseases caused by helminthic parasites is gnathostomiasis, a disease caused by Gnathostoma spp. Topical application of the natural ergot alkaloids ergocristine, alpha-ergocryptine and ergocornine lowered intraocular pressure in alpha-chymotrypsin-induced ocular hypertensive rabbits in a dose-related fashion, with ergocristine displaying the greatest intraocular pressure-lowering effect.

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Prognosis of severe infections is dependent upon timely and correct diagnosis and appropriate therapy. Particular attention is paid to the subject matter of courses in analytical chemistry and its future improvement, with special focus on problems related to training specialists in analytical chemistry at universities and other institutions of higher education. Here, we report that the factors governing the degradation of IFI16 and its colocalization with ICP0 are distinct from those of promyelocytic leukemia protein (PML), a well-characterized ICP0 substrate. There is still a great deal of development in the area of tissue characterization/mapping, so these protocols have been in general left as optional.

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Mycosis fungoides and Sezary syndrome: therapeutic approach and outcome in 113 patients. In addition, DEK appears to participate in multiple cellular processes, including transcriptional repression, mRNA processing, and chromatin remodeling. The Catquest-9SF includes questions concerning vision-associated problems in everyday life, general satisfaction with vision, and difficulties performing activities. Mucosecretor adenocarcinoma of the lung with pleural involvement presenting as a pneumothorax. In particular, recent developments in nanofibrous scaffolds, nanobiomaterial composites, hydrogel systems, laser-fabricated nanostructures and cell-based bioprinting methods to produce scaffolds with nanofeatures for tissue engineering are discussed.

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Femtosecond time-resolved absorption processes in lithium niobate crystals. Likewise melatonin prevented iNOS activation and reduced the concentration of products from both enzymes, PGE(2) and nitric oxide. We identified a gene of maize (Zea mays L.) that is transcriptionally activated in decapitated coleoptiles.

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Birds were injected intramuscularly with 0, 3, 10, and 30 mg/kg body weight of naloxone hydrochloride. Unambiguous identification of the TLC spots is, however, often a problem. Midbrain GABAergic neurons regulate multiple aspects of behavior and play important roles in psychiatric and neurological disease. Mechanistic studies have revealed how miRNAs contribute to heart disease pathogenesis.

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Electro membrane isolation of nerve agent degradation products across a supported liquid membrane followed by capillary electrophoresis with contactless conductivity detection. It offers an idiographic assessment of depression that is complementary to questionnaire measures, particularly by generating hypotheses about target problems and dysfunctional beliefs within a cognitive-behavioural case-formulation.

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Quantitative image analyses showed that HDAC2 IR correlated positively with 5-mC IR while these markers were shown to colocalize in the nucleus of hippocampal cells. Practically speaking, the combinations of DNA damaging agents with the inhibitors of anti-apoptosis would increase the efficacy of anticancer therapy. Human UGT isoforms were used to determine glucuronidation rates.

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A model discriminating experimental design approach for fed-batch processes has been developed and applied to the fermentative production of L-valine by a genetically modified Corynebacterium glutamicum strain possessing multiple auxotrophies as an example. Most of the papers find the technique valuable for evaluation of nasal patency. Based on the N-terminal amino acid sequences of fission yeast and human Pot1, two Pot1-like proteins (AtPOT1-1 and AtPOT1-2) have been identified in Arabidopsis thaliana, but neither of them has been characterized yet. Dexamethasone and cardiac potassium currents in the diabetic rat.

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Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Many studies have investigated associations between the glutathione S-transferase M1 (GSTM1) null polymorphism and risk of prostate cancer, but the impact of GSTM1 in people who live in Asian countries is still unclear owing to inconsistencies across results. The initial insult in adipose inflammation and insulin resistance, mediated by macrophage recruitment and endogenous ligand activation of Toll-like receptors, is perpetuated through chemokine secretion, adipose retention of macrophages, and elaboration of pro-inflammatory adipocytokines. Prevention of hip lag screw cut-out in osteoporotic patients: rationale and review of the literature. We found that the atypical receiver sequences of HP1043 and HP1021 are not crucial for the function of these response regulators.

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Recent findings indicated that the persistence of LTM requires late-phase protein synthesis in the dorsal hippocampus. The proposed NAS-based calibration method was successfully applied to the simultaneous analyses of anthazoline and naphazoline in a commercial eye drop sample. Oral hygiene practices and dental service utilization among pregnant women.

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Distributions of nematode egg counts for 11 of the 12 cattle populations sampled were well described by a series of negative binomial distributions. This indicates that there exists a certain relation between abnormalities of the central noradrenergic systems and hypothalamic-pituitary-adrenal axis in patients with major depression. Concomitant with ERK activation, SDF1alpha also activated the downstream transcription factor Ets, a substrate for ERK phosphorylation. Adamantinoma-like Ewing family tumor of soft tissue associated with the vagus nerve: a case report and review of the literature. Forty pseudophakic eyes of 35 patients with PCO of varying intensity were examined before and after Nd:YAG laser capsulotomy.

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Serum concentrations of leptin and glucose in the SG were significantly lower than those in the NG. The nurse is clinically responsible for the donation session, with the care of donors and the safety of the blood being their main priority. Our patients further highlight this potential for normal cognitive outcome and draw attention to possible skewing of unfavorable prognosis for the final developmental outcome in this population.

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The microscopic observation drug susceptibility (MODS) assay has been evaluated in different parts of the world to determine whether it can give comparable result to commercial liquid techniques. From late 2003, the National Blood Service provided 80 to 90 percent of fresh-frozen plasma (FFP) and plasma for platelet (PLT) pools from male donors.

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The degree of contraction was determined utilizing profiles of the specimen edges obtained with the help of stereo measurements. First, large numbers of independent MCM trajectories were carried out and the lowest free energy docked configurations identified.

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These assays, which exploit the specific activity of the label, give a very high sensitivity and good reproducibility. The methods enabled remarkably detailed information on bone microstructure and remodeling to be gleaned from tiny fragments of bone. Registry of the urogynaecologic procedures involving implant in the Czech Republic during the year 2007 To deal with these issues, the design of an innovative monitoring system should be based on the integration between different sources of knowledge and information. This article describes a restorative alternative for fixed implant-supported reconstructions, consisting of a CAD/CAM-generated framework and CAD/CAM-generated all-ceramic cement-retained restorations.

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Additionally, the obstetrician will need to monitor fetal status and help to determine the best timing for delivery. In this Letter, a system measuring the optic axis azimuth was built using the laser feedback method that the polarization state of laser output is linearly polarized when optic axis azimuth is consistent with the initial direction of the laser polarization, otherwise elliptical polarization will be observed. AMYLOIDOSIS IN THE MATERIAL OF THE DEPARTMENT OF PATHOLOGY OF THE INSTITUTE OF TUBERCULOSIS IN WARSAW OBSERVED DURING THE PERIOD 1945-1962 We found that supportive feeder cells secrete growth factors required for both hESC survival/proliferation and blocking hESC spontaneous differentiation to achieve self-renewal.

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NEUROPSYCHIC STUDY OF THE MOTHERS OF CHILDREN WITH GRAVE CONGENITAL EPIDERMOLYSIS BULLOSA The platelets produced from these megakaryocytes also expressed elevated levels of HO-1. The method of investigation used had an qualitative approach, of the descriptive and exploratory kind, applying semi structured interviews to five nurses of ICU at a General Hospital of the south area of Rio Grande do Sul.

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Genetic basis of dental occlusal variations in northwest Indian twins. Disease modifiers, including transient or permanent host-related factors, may also influence the development and severity of acute abscesses. Furthermore, the cumulative effect of age-related immune senescence, superimposed on this enhanced risk of infections, can lead to serious and life-threatening infections in elderly patients with DM. Theoretical multiplex gain in a UV/VIS Hadamard transform spectrometer utilizing a uniformly imperfect encoding mask.

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AN EXPERIMENTAL INVESTIGATION OF PATTERN DEVELOPMENT IN LETHAL SPOTTING AND BELTED MOUSE EMBRYOS. Zeolitized tuffs in pedotechnique for the reclamation of abandoned quarries. In each of 4 monkeys, 1 central incisor and 2 first molars in the maxilla and the mandible were selected for experimentation.

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This work provides a framework by which the temporal effects of appetite modulating agents can be recorded simultaneously within hypothalamic and brainstem feeding centres. A monoclonal antibody was selected that recognizes the ligase IIIalpha BRCT domain, but not the other BRCT domains, and was used to capture the relevant ligase IIIalpha BRCT complex.

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The complex resulting matrix, collecting the relative abundance of the 23 selected constituents for each sample, has been input into the SOM software adapted and optimized from the Kohonen approach described by one of the authors. SCP3 is thus linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes. The solvent effect on the photostability of Hg(II) dithizonate in daylight and under laser irradiation has been confirmed and benzene found to be the best solvent to use in photometric work with Hg(II) dithizonate. Nine year-old male patient, who underwent bone marrow transplantation because of acute myelogenous leukemia, presented with fever and dry cough three days after the procedure.

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Disturbed calcium metabolism in a patient with bipolar disorder and impaired renal function. These changes in PKC activity suggest that PACAP and VIP are capable of activating this enzyme in cerebral cortex of chick. trilobatum was found to be more susceptible against the larvae of Ae. In batch experiments, the adsorption property of biofilm-attached clinoptilolite did not show substantial difference from that of natural clinoptilolite, indicating that bioregeneration became completely achieved without any regenerant in the AS. The intervention included peer-led educational sessions and an oral exam by the school nurse who also provided brief tobacco cessation counseling.

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The immediate and definitive restoration of teeth after direct pulp capping should always be aimed for. Here, we describe a new modular satellite (SAT) drug interaction between fluoxetine and alprazolam vector system that supports N- and C-terminal fusions to five different autofluorescent tags, EGFP, EYFP, Citrine-YFP, ECFP, and DsRed2.