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Actios (Acyclovir)
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Acyclovir

Actios is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) to treat and prevent the reoccurrence of herpes simplex virus (HSV) episodes (including genital herpes) and to treat varicella zoster virus (VZV) diseases (including chicken pox and shingles). Actios is approved in different formulations and strengths for use in specific populations, including in people who are immunocompromised. HSV and VZV infections are opportunistic infections (OIs) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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This medication is used to treat "cold sores/fever blisters" (herpes labialis). It can speed up healing of the sores and decrease symptoms (such as tingling, pain, burning, itching). Actios belongs to a class of medications known as antivirals. It works by stopping the growth of the virus. This medication does not cure herpes, and it does not prevent passing the infection to someone else. It does not prevent a future occurrence. OTHER This section contains uses of this drug that are not listed in the approved US professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat genital herpes. Other medications taken by mouth may be more effective for genital herpes. Discuss your treatment options with your doctor. This medication does not cure herpes or prevent infection of sexual partners.

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Changes in first-line cART regimens and short-term clinical outcome between 1996 and 2010 in The Netherlands. 221 hypertensives (cases) and 221 normotensives (controls) were interviewed, subjected to a physical examination, and provided blood for biochemical and genetic tests. Q-body formation is a dynamic process that actively manages the metastable state of the protein fold through small heat shock proteins and the Hsp70-Hsp90-Hsp110 proteostasis system to promote cellular fitness under both physiological and stress conditions. Multiple linear regressions (MLR) was employed to model the relationships between molecular descriptors and biological activities of molecules using stepwise method and genetic algorithm as variable selection tools. Laparoscopy-assisted creation of a loop ileostomy is an effective method for temporary fecal diversion in patients undergoing anorectal surgery.

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Analysis of the ANP and BNP promoters has contributed in a major way to our present understanding of the key regulators of cardiac development. To investigate the effects of small interfering RNA (siRNA)-mediated inhibition of Class I phosphoinositide 3-kinase (Class I PI3K) signal transduction on the proliferation, apoptosis, and autophagy of gastric cancer SGC7901 and MGC803 cells. Experimental animal infections reproduced typical highly pathogenic AIV infection symptoms and pathology.

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The diagnosis of clear cell renal cell carcinoma on morphologic grounds alone is generally straightforward, but challenging cases are not infrequent. Global and local music perception in children with Williams syndrome.

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To test this hypothesis, cruciform biaxial connective tissue samples that display distinctly different material properties (bovine pericardium, fish skin), as well as model textile laminates with predefined fibrous orientations, were repeatedly tested with decreasing sample arm lengths. Intravenous digoxin blunts the rise of inotropy induced by isometric exercise: a noninvasive study in healthy volunteers. SOCIO-MEDICAL BACKGROUND FOR WORK IN MATERNAL WELFARE INSTITUTIONS Ultra-low detection limits, two orders of magnitude lower than those achievable with spectrophotometric detection, were found. Reversion of these methylation patterns could thus lead to a more targeted therapy and are currently under clinical investigation.

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Clinical and prognostic subforms of new daily-persistent headache. Increased mutant fraction was not detected following exposure to a magnetic field alone, or after sham exposure. The relationship between reactive oxygen species (ROS) production and cell membrane mobility was investigated to clarify the pro-oxidant mechanism of curcumin and tetrahydrocurcumin (TH-curcumin). Plaque was evaluated using the Rustogi Modified Navy Plaque Index.

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The transdifferentiation was a direct phenotypic change from RPE cell to neurons without cell differentiation. In addition, weight gain after age 15 was negatively associated with cognition at 26. Respondents to this survey of Canadian physicians treating patients with severe head injury reported published evidence as being the most significant factor affecting use of a therapy.

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A systematic review of the basic science and clinical literature is presented. Radial nerve morbidity in radial artery free flaps: harvest of cephalic vein versus venae comitantes.

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Tumor metastasis is a critical determinant of death from cancer. Geographical inequalities of mortality by income in two developed island countries: a cross-national comparison of Britain and Japan. The building bricks of this toolbox are: (1) a new algorithm for robust, accurate, and fast estimation of the symmetry plane of grossly symmetrical surfaces, and (2) a new algorithm for the fast, dense, nonlinear matching of surfaces.

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Radon measurements were performed in a sample of 411 one-family houses in seven villages located in the southern area of Bergamo and Brescia. In this study we determined whether extracts of Emblica officinalis fruits display activity of possible interest for the treatment of rheumatoid arthritis and osteoporosis by activating programmed cell death of human primary osteoclasts.

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A high degree of resilience can help patients to adapt to their situation and to resume their everyday life. These inflammatory signals originate from the immune system, the largest source of cell-derived regulatory signals and such immunological signals to the bone results in secondary osteoporosis and bone destruction. Using the experimental autoimmune encephalomyelitis (EAE) model of the human CNS autoimmune disease multiple sclerosis, we demonstrate that gamma delta T cells are important regulators of CNS inflammation. The V249I polymorphism revealed no association with tumor grade and stage, the presence of extrahepatic metastasis or the degree of fibrosis in non-tumorous tissue.

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The results indicated that adenine was apparently not susceptible to microsomal N-oxidation. We reviewed the current and projected nurse practitioner workforce, and we summarize the available evidence of their contributions to improving primary care and reducing more costly health resource use. Cellular DNA, viral DNA (both single and double stranded forms), cellular RNA, and RNA arising as a result of viral stimulus can be differentiated.

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The development of focused population-based preventive strategies is likely to improve functional independence in the aged. A well-defined cathodic wave and one anodic peak were observed for the pyrantel pamoate in the entire pH range. Use of cryptograms for characterization of strains of the Bacillus thuringiensis-Bacillus cereus group. Acute myeloid leukemia (AML) is an aggressive hematologic neoplasm.

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The results indicate that mendelian transmission of a single locus is not sufficient to explain the distribution of premenopausal breast cancer seen. Soluble sugar levels must be closely regulated in germinating seeds to ensure an adequate supply of energy and building materials for the developing seedling. Due to the high affinity of these compounds to the cannabinoid receptors, their effective dose is lower than that of the marijuana products resulting in a low concentration of the excreted metabolites accompanied by a higher psychoactive potency. The anatomical defects and length-tension dysfunction of anal sphincter complex muscles in patients with fecal incontinence were evaluated. Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40.

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Therefore, it is essential that the pure target protein maintain its original biological (or functional) behavior over an extended period of storage which may range from weeks to years. ARTHROPOD-BORNE VIRUS INFECTIONS OF ABORIGINES INDIGENOUS TO AUSTRALASIA.

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Patients with an RMI higher than 450 were referred to tertiary cancer centers. Factors associated with the timing of antenatal care seeking in Bangladesh.

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Effect of different doses of ionizing radiation on the binding of prostaglandin E2 in mouse tissues However, a subgroup of patients is refractory at the cytogenetic level. The titration curves have sharp breaks, suitable for analytical use, and these are discussed, in the case of promethazine hydrochloride, as functions of various parameters such as pK(a), the solubility of the product and the enthalpy of neutralization (determined in this work). PATELLAR LUXATION AND ITS SURGICAL TREATMENT BY THE ROUX-HEINEKE METHOD. In comparisons to conventional clone library screening and Sanger sequencing, the TaqMan assay approach provided similar accuracy but higher sensitivity with cost and time savings.

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Between January 2005 and December 2011, cervicovaginal smears (98,594) with a diagnosis of ASC-H, LSIL, LSIL/ASC-H, or HSIL were re-evaluated to determine the prevalence of future lesion development. Nursing that works: how to ask for help and increase your odds of getting it. We hypothesized that the covalent linkage of a known tumor antigen peptide to beta-2-microglobulin (beta2m) would increase peptide immunogenicity and, therefore, in vivo effectiveness as an antitumor vaccine in BALB/c mice. However, the original SSCP protocol is generally large-formatted, which is both time and reagents consuming as well as cumbersome. What do social scientists learn by employing qualitative data analysis software (QDAS) in the service of multi-method designs?

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We have shown that the shape of the sonographic image of breast cancer is similar to the shape of its hyaluronan extracellular matrix. Three major groups of tumors with different elastic properties relative to brain tissue could be differentiated. Evaluation of caspofungin or micafungin as empiric antifungal therapy in adult patients with persistent febrile neutropenia: a retrospective, observational, sequential cohort analysis. Psychometrics of a self-report version of the Child and Adolescent Dispositions Scale. After classification according to each staging system, the long-term survival of different stages was compared.

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Coronary sinus lead placement in the posterior or lateral coronary sinus branch represents an acceptable alternative approach for pacemaker lead placement in these patients. In fibroblast cultures, enhanced mRNA expression of ET-1, ET(A) and ET(B) was observed after CsA treatment at the concentrations of 10 and 100 ng/mL.

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Using flow cytometry to determine the viability of Cryptosporidium parvum oocysts extracted from spiked environmental samples in chambers. Use of the Australian Childhood Immunisation Register for vaccine safety data linkage. Iridocorneal angle assessment is essential in glaucoma diagnosis and management, and gonioscopy remains the clinical reference standard for its evaluation. The moment the index crosses the threshold is considered as the moment of seizure onset. Here, we show that a strict reverse relationship also exists: the harmonic admittance of a periodic system of electrodes may always be expressed as the ratio of two determinants, which have been specifically constructed to describe the eigen-modes of the open- and short-circuited systems.

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Histological complete response in a case of advanced gastric cancer treated by neo-adjuvant chemotherapy with S-1/CDDP This study used a Bayesian approach to explore the utility of routinely collected and sparse TDM data (1 sample per patient) for carbamazepine (CBZ) monotherapy in developing a population pharmacokinetic (PPK) model for CBZ in pediatric patients that would allow prediction of CBZ concentrations for both immediate- and controlled-release formulations. In the first patient, clinical judgment rejected the suspicion of HIT despite a positive screening assay, and treatment for the alternative diagnosis of post-transfusion purpura was correctly initiated.

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Exclusive inactivation of a single Pax6 allele in the lens recapitulates the Small-eye lens and corneal defects, while only mildly affects iris morphology in a non-cell-autonomous fashion. Adherence of yeast and filamentous forms of Candida albicans to cultured enterocytes. Lysine-to-arginine substitutions in Rep1 and Rep2 that inhibited their sumoylation perturbed plasmid inheritance without affecting Rep protein stability or two-hybrid interaction between Rep1 and Rep2. We found significantly increased IGFBP-3 expression levels in the psoriatic group compared with levels in patients with other, nonproliferative inflammatory skin diseases, and we demonstrated differences in distribution pattern before and after systemic treatment with Mtx or CsA. Fifty patients with unilateral mTLE (26 left- and 24 right-sided mTLE) were recruited in the present study.

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