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Losart (Losartan)
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Losartan

Losart significantly reduced mean blood pressure in sham-operated rats and decreased mean blood pressure and left ventricular end-diastolic pressure in myocardial infarction rats. We compared the effect of an ACE inhibitor, enalapril, and an angiotensin II antagonist, Losart, on total malodialdehyde in blood and the urinary excretion of certain eicosanoids and their metabolites (TxB(2), 6-keto-PGF(1alpha), bicyclo-PGE(2) and 8-isoprostane) in experimental adriamycin-induced nephrotic syndrome in rats.

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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Losart is used alone or in combination with other medications to treat high blood pressure. Losart is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). Losart may not decrease the risk of stroke in African Americans who have these conditions. This medication is also used to treat kidney disease in people who have type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) and high blood pressure. Losart is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

High blood pressure is a common condition, and when not treated it can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

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Technical tips for fixation of proximal humeral fractures in elderly patients. his work points to HGF as a pro-adhesive factor in cell adherence to the bone marrow matrix protein fibronectin, an event known to promote cancer cell survival and drug resistance. The PDI chromophores are located in opposite strands of the hairpin base pair domain opposite abasic sites and are either adjacent to each other or separated by a variable number of AT or GC base pairs.

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Presence of paraneoplastic antibodies in non-carcinomatous patients with neurological involvements of unknown cause. Neuroanatomy and neurophysiology of the locust hypocerebral ganglion. The aim of the present study was to evaluate the long-term sealing ability (both apical and coronal) of an epoxy resin root canal sealer (AH26) when used with different gutta-percha obturation techniques. The phantom is a robust standardized test object for use in a multicenter trial. To resolve this adverse event it is essential to discontinue mesalazine treatment.

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Five genes encoding phenylalanine ammonia-lyase (PAL), cinnamate 4-hydroxylase (C4H), chalcone synthase (CHS), flavanone 3-hydroxylase (F3H) and dihydroflavonol reductase (DFR) of the phenylpropanoid biosynthesis pathway were partially resequenced in 16 diverse barley reference genotypes. Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis. Therapeutic management took into account the results of all modalities, and all patients were followed up for at least 6 months and reviewed by the same surgeon. For the most part, this technique has mainly been applied to screen specific target moieties. Acids conjugated to various phenothiazine derivatives are titrated directly with sodium hydroxide, by means of an automatic thermometric titrimeter.

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In 17, one or more of the above mentioned abnormalities was or had been present. Comparison of the two structures highlighted the plasticity of the carbohydrate-binding site expressed in terms of the conformational change in lactose binding. Although iodine 123 15-(p-iodophenyl)-3-(R , S) methylpentadecanoic acid (BMIPP) can assess abnormal utilization of fatty acid in the diseased myocardium, the prognostic value of BMIPP imaging at rest in patients with known or suspected coronary artery disease (CAD) remains unclear.

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Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters. THE VALUE OF THE ESOPHAGEAL LEAD IN THE DIFFERENTIAL DIAGNOSIS OF TACHYCARDIA

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Metronomic therapy with cyclophosphamide and piroxicam effectively delays tumor recurrence in dogs with incompletely resected soft tissue sarcomas. Acceleration/ejection time ratio in the fetal pulmonary artery predicts fetal lung maturity. Although coherence between entorhinal and hippocampal theta activity has been found to influence memory formation, it remains unclear whether these two structures can generate theta independently.

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Furthermore, we found that dynein and kinesin do not work against each other in vivo during peroxisome transport. The stability study was carried out on three samples sets: (a) polymer samples irradiated and stored in air, (b) polymer samples irradiated and stored under vacuum, and (c) polymer samples irradiated under vacuum and stored in air.

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Antimicrobial and chemoattractant activity, lipopolysaccharide neutralization, cytotoxicity, and inhibition by serum of analogs of human cathelicidin LL-37. In the current study the pattern of vascular supply of the proximal humerus was studied in six cadavers by the corrosion technique. The conclusions are reached that prosthetic fitting and training should be initiated very early in life and that co-operation of the parent is essential to successful habilitation of a child with congenital limb anomalies. We have implemented our method, which we have named G-hash, and have demonstrated its utility on large chemical graph databases. In fact, allogeneic transplantation may replace the whole immune system.

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Contemporary results of endovascular repair of abdominal aortic aneurysms: effect of anatomical fixation on outcomes. The same effect was noted for the clearance values of these solutes. In addition, different forms of schisis may affect different locations in the macula (foveal vs parafoveal), and, in most eyes, the schisis involves the entire foveomacular region.

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The results of RM analysis of biofilms are in good agreement with data obtained by confocal laser scanning microscopy (CLSM). Adiponectin, an adipocyte-derived peptide, improves insulin sensitivity, has antiinflammatory and antiatherogenic effects, and is associated with a lower risk of ischemic heart disease (IHD) and type 2 diabetes.

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Private acupuncture offices in the greater Seattle, Washington, metropolitan area. Orthopedic nano diamond coatings: control of surface properties and their impact on osteoblast adhesion and proliferation. The clinical and research utility of the various measures are discussed. This article describes how two nurses developed informational materials to help busy nurses give patients the information they need to set their minds at rest about telemetry. A significant proportion of patients with major depressive disorder (MDD) do not improve following treatment with first-line antidepressants and, currently, there are no objective indicators of predictors of antidepressant response.

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Recent progress in mapping quantitative growth traits (QTL s) in rice yields insights into mechanisms of plant growth, hints at genomic signatures of the domestication process and promotes the prospect of agricultural improvement via introgression of beneficial variants. The present study examines an alternative approach to the study of cytokine gene function in atopy, focusing instead upon T cell transcription factors (TFs) which play a role in the regulation of multiple cytokine genes. More generally, our results raise the possibility that spectrin-like repeats may enable some members of the plakin family of cytolinkers to laterally bind and stabilize actin filaments. Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor.

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The difference in enantioselective free energy between the aglycone CSP and the teicoplanin CSP was in the range between 0.02 and 0.97 kJ mol(-1) for these beta-lactam stereoisomer separations. Ten human inferior alveolar nerves were inspected microscopically to determine the fascicular characteristics. Another piece in the maddening puzzle of declining steroidogenesis in aging Leydig cells. Application of ridge regression to quantify marginal effects of collinear soil properties on phytoaccumulation of arsenic, cadmium, lead, and zinc. The relative effectiveness of the streamlined designs was found to increase with increasing particle size and increasing flow, with a maximum improvement in emitted dose of 1.9-fold.

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Ten young, male, entire small ruminants (seven kids and three lambs) with obstructive urolithiasis, which were presented within three days of complete blockage and before rupture of the urinary bladder and urethra, underwent a minimally invasive surgical tube cystotomy through the left paralumbar fossa. There has been increased interest in the possible role of human cytomegalovirus (HCMV) in carcinogenesis during the last decade. The consequences of the restrictive abortion laws in Brazil are also discussed. An extensive range of experiments was performed on both a series of solid disks and a series of laminated disks under a range of normal clamping pressures.

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The discovery of the key role of Toll-like receptors (TLRs) in initiating innate immune responses and modulating adaptive immunity has revolutionized our understanding of vertebrate defence against pathogens. A newly recognized fungal pathogen in immunosuppressed patients. The determination of mother cell-specific mating type switching in yeast by a specific regulator of HO transcription. Grape seed extract suppresses lipid peroxidation and reduces hypoxic ischemic brain injury in neonatal rats. Stearoyl-CoA desaturase (SCD), the rate-limiting enzyme in monounsaturated fatty acid synthesis, has recently been shown to be the critical control point regulating hepatic lipogenesis and lipid oxidation.

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To evaluate whether disease severity influences quality of life using the Incontinence Quality of Life questionnaire and to determine the factors that effectively reflect disease severity in women with stress urinary incontinence (SUI). Hand position trajectories were recorded with an electromagnetic sensor. All of the other coagulation and fibrinolysis parameters (including prothrombin time, activated partial thromboplastin time, fibrinogen and D-dimer) were comparable between the three groups.

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Digital mammography using iodine-based contrast media: initial clinical experience with dynamic contrast medium enhancement. In the same way, CYP1-activatied prodrugs are categorized into four groups: benzothiazoles, flavonoids, stilbenes and alkylating agents. Modelling study using data from a prospective cohort, EPIC-Norfolk (European Prospective Investigation of Cancer-Norfolk). The calculated pH values agree well with those experimentally observed.

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Does the pharmaceutical industry manufacture diseases as well as drugs? Activin A induction of erythroid differentiation sensitizes K562 chronic myeloid leukemia cells to a subtoxic concentration of imatinib. However, the Stabilis cage is not favored in extension and lateral bending because of insufficient stabilization. Glycosylation consensus sequences-disrupted mutants showed the apical localization as the wild type, whereas the apical-selective expression disappeared when disulfide bonds could not be formed. This study was designed to determine whether inspiratory resistive training could improve the exercise performance of patients with severe chronic airflow limitation who had already received optimum conventional therapy with bronchodilators and physiotherapy.

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Outcomes of various screening strategies in retinopathy of prematurity are not well reported. Ammonia plasma treatment can be used to defluorinate the PTFE, decreasing the dynamic contact angle. How malaria has affected the human genome and what human genetics can teach us about malaria. In three models, free radical load of different origin, lipidperoxide load, application of a glutathione depletor or a prooxidant agent, was introduced.

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This report highlights the presence of unidentified novel mechanisms of antidepressant-induced galactorrhea and other possible contributors. This schedule was repeated twice, with a 1-week split, for a total RT dose of 60 Gy during 7 weeks for 25 patients.

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Fluorescence emission was collected orthogonally to the light-sheet through a gradient-index lens assembly and a coherent fiber bundle. Recovery course of excitability in a single neurone of Onchidium verruculatum. With knowledge of the energy expended during wheelchair propulsion, nutritional recommendations can be provided for individuals in their early stages of rehabilitation and for habituated wheelchair users. Only strains B86 and 35398 had substantial anti-hepatitis B e antigen activities.

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We also studied the relationship to cancer testis (CT-X) antigens that co-localize with L1CAM on chromosome Xq28, a region that is often activated in human tumors. The use of DNA constructs encoding this cytokine may be a way of achieving maximum therapeutic benefit with minimum toxicity. Corrosion of dental alloys in vitro by differential oxygen concentration.

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The module was systematically calibrated with experimental data from various batch experiments, a full-scale WWTP and a pilot plant treating Swiss municipal wastewater. Setting properties and sealing ability of hydraulic temporary sealing materials.

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Most studies of animal cognition focus on group performance and neglect individual differences and the correlational structure of cognitive abilities. This phenomenon can be evaluated by a number of methods (microscopic observations, viscometry, light measurements) which cannot be applied simply to in vivo measurements. Importantly, modulation of isoform production of cell death proteins via pharmaceutical manipulation of alternative splicing may open up new therapeutic avenues for the treatment of disease. The diagnosis and management of patients with giant cell arteritis. We retrospectively evaluated the records of 975 patients, ranging in age from 0 to 88 years, who displayed facial palsy at Kyung Hee Medical Center between January 1986 and July 2005.

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Determination of rutin and other flavonoids by flow-injection/adsorptive stripping voltammetry using nujol-graphite and diphenylether-graphite paste electrodes. The study was carried out in a non-destructive way by the SPI MRI method.

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The study subjects were 52 persons (88 eyes) with no previous medical history. Strongly recommended indications for eradication therapy include gastroduodenal ulcer disease, giant fold gastritis, lymphocytic gastritis, autoimmune gastritis, gastric MALT lymphoma, atrophic gastritis, corpus-predominant gastritis, post gastric cancer resection and patients who are first degree relatives of gastric cancer patients. In this work, datasets of water and carbon fluxes measured with eddy covariance technique above a summer maize field in the North China Plain were simulated with artificial neural networks (ANNs) to explore the fluxes responses to local environmental variables.

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Bioinformatics resources for the study of gene regulation in bacteria. The tumor extension into the renal pelvis, however, has been found in several reports. The study complements existing analyses examining sound radiation in static- and detached-flap configurations. Changes and tracking of fruit, vegetables and sugar-sweetened beverages intake from 18 months to 7 years in the Norwegian Mother and Child Cohort Study.

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Murine models of atherosclerosis rely on the induction of hyperlipidemia for vascular lesions to form, but the pathogenic contributions attributed to different lipoprotein populations are not well defined. Kinase activity is observed when the heme is a ferrous five-coordinate high-spin or six-coordinate low-spin CO or NO complex but is strongly inhibited in the oxy complex. Dejerine-Sottas syndrome and vestibular loss due to a point mutation in the PMP22 gene.

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Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice. This review presents the current status of antiviral therapy of, and highlights the challenges presented by, the threat of pandemic influenza. Recently, a variant in the human bdnf gene, resulting in a valine to methionine substitution in the prodomain, has been shown to lead to defective regulated secretion from neurons and memory impairment. A distinct restoration effect on cell motility was observed after incubating with DDSW. Changes in circulating miRNA profiles have been associated with different diseases.

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However, in the case of the e-cigarette fluid, the composition is not properly labeled: additives like nicotine and flavors vary between and within brands and contamination with various chemicals has been detected. GFP cell-marking provided direct evidence of the BM cells participation in liver regeneration after hepatectomy, where the majority was committed to sinusoidal endothelial cells probably through endothelial progenitor cell mobilization.

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Cisplatin (50 mg/m(2), intravenously on day 1) and S-1 (80-120 mg/m(2), orally twice a day between days 1 and 14) were administered every 21 days for 6 cycles in patients with advanced or recurrent uterine cervical cancer. Conkunitzin-S1 (Conk-S1) is losec doses of prozac a 60-residue neurotoxin from the venom of the cone snail Conus striatus that interacts with voltage-gated potassium channels. The relationship between worker body size and the shape of their body parts was explored in the polymorphic ant, Solenopsis invicta.

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Access to objective radiographic bone density values should constitute side effect of omeprazole 20 mg a valuable supplement to subjective bone density evaluations prior to implant placement. Novel water-soluble bacteriochlorophyll derivatives for vascular-targeted photodynamic therapy: synthesis, solubility, phototoxicity and the effect of serum proteins. The panelists highlighted the need for education and awareness among health-care providers to help people understand options for preserving fertility, the need for technologic advances, the lack of data on long-term consequences of fertility preservation, and emerging ethical and social questions. These findings confirm the presence of brain RAS activation in LKR and its contribution to the central control of pressor response to cadmium ICV.

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Effect of transcranial magnetic stimulation on Parkinson motor function--systematic review of controlled clinical trials. She complained of colicky abdominal tab armod-150 pain in the left upper quadrant area and dizziness when she assumed an upright posture. Secondly, to investigate whether estimation of muscle fiber conduction velocity can help identifying the propagating and non-propagating nature of genuine reflexes and crosstalk respectively, thus allowing a more valid assessment of the NWR. An initial two decades period (1954-1973) has contributed to the biochemical individualisation of peroxisomes as a new class of subcellular organelles (de Duve, 1965).

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The 85th percentile BMI defined at-risk-for-overweight and the 95th percentile BMI defined overweight. Structural perturbation by temperature or low concentrations of denaturants leads to enhancement of its chaperone-like activity. Biliary drainage by endoscopic choledochoduodenal fistulotomy in patients with papillary carcinoma. All residents of a convenience pitavastatin vs simvastatin 80 sample of 8 nursing homes of more than 80 beds were eligible if they resided at least 1 month in the nursing home and took 4 or more different medications. Polycyclic aromatic hydrocarbons (PAHs) are an ubiquitous class of compounds in the environment, mostly generated by anthropogenic processes.

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Application of iontophoresis significantly increased the permeation of all the tested peptide dendrimers across human skin in a molecular weight-dependent manner compared to simple passive diffusion. The program aims to improve case outcomes by consolidating resources to facilitate assessment and treatment planning. As proved by electron paramagnetic resonance, nNi(OH)2 may induce the generation of hydroxyl radical in the fish, and nNi(OH)2 as concentrated in the fish may incur redox reaction and produce redox proceptin dosage forms metabolic intermediates.

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Novel epidemiologic evidence for the association between fermented fish sauce and esophageal cancer in South China. EFFECTS OF SOME PHARMACOLOGICALLY ACTIVE AMINES ON THE UPTAKE OF ARYLALKYLAMINES BY ADRENAL MEDULLARY GRANULES. Optimal and overdoped gastrimut vs nexium films are qualitatively and quantitatively different from underdoped films. Therefore, RILP represents probably an important factor for all endocytic routes to lysosomes.

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The increase in the COX activity was established in the EH, with the highest values found in the BI, somewhat lower in the RIA, and the lowest in the TIA group, respectively. Effectiveness research had not had sufficient public or private funding to produce the information needed to facilitate evidence-based health care improvement. Ingenuity Pathway Analysis mainly revealed canonical pathways of cellular immune response and cytokine signaling as well as a broad range of processes in cellular and organismal growth, proliferation and filmet drug identification development, cell signaling, biosynthesis and metabolism. Other possible mechanisms contributing to hypercalcemia and pulmonary calcinosis in children with acute leukemia include bone resorption due to marrow infiltration, immobilization syndrome, renal failure, and administration of calcium, phosphate, or bicarbonate. A dramatic effect of the electronic and structural shape of the inhibitors on selectivity was demonstrated, confirming the non-zinc-bonding mode of inhibition of this class of sulfonamides.

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As a consequence of the microtubule omnexel generic drugs collapse, cytoskeletal structures as well as intermediate filaments break down, leading finally to a contraction of vascular endothelial cells. Development of acetylcholine sensitivity in muscle following blockage of nerve impulses. Recent advances were made in understanding the tissues in which different components of the photoperiod pathway act to regulate floral induction.

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