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Modafinil (Modatec) is a wake-promoting drug characterized by cognitive enhancing abilities. Modafinil (Modatec) is a wake-promoting drug characterized by cognitive enhancing abilities. Long-term efficacy and safety of modafinil (Modatec((R))) for the treatment of excessive daytime sleepiness associated with narcolepsy.

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The biological tissue is generally distinguished from the inorganic matrix by the presence of a significant population of protons in the solid components that are well connected by dipolar spin couplings. Phenylketonuria, the inborn errors of metabolism, and clinical research--1971. However, the underlying mechanisms for these changes have not been resolved. We performed proteomic studies on lung cancer cells to elucidate the mechanisms that determine histological phenotype. Most seriously wounded US Army casualties from the Iraqi theater of operations come through Walter Reed Army Medical Center on their return to the United States.

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Endocavitary structures in the outflow tract: anatomy and electrophysiology of the conus papillary muscles. An experimental demonstration of the existence of a vitamin which promotes calcium deposition.

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The two provincial policies present different approaches to support the implementation of related programs. Autochthonous cases of canine babesiosis in the canton Solothurn The vast majority of extracellular proteins are exported from mammalian cells by the endoplasmic reticulum/Golgi-dependent secretory pathway.

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Dentine hypersensitivity: effect of interactions between metal salts, fluoride and chlorhexidine on the uptake by dentine. Recent studies indicate that methylphenidate alters gene expression in striatal neurons. The physical examination, including careful neurologic examination and notation of any apparent anatomic abnormalities, helps diagnose congenital problems, infection, and conditions contributing to respiratory compromise.

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Acute intestinal obstruction in postoperative ventral hernia unconnected with strangulation The results we present suggest PacBio data will be of immense utility for the development of genome sequence assemblies containing fewer unresolved gaps and ambiguities and a significantly smaller number of contigs than could be produced using short-read sequence data alone. A 68-year-old woman presented with cephalgia, left temporal hemianopsia, and ptosis. Computerized BCN was used to estimate probability of non-SLN positivity and compared with actual probability after grouping into deciles.

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Corrosion of dental amalgams in solutions of sodium chloride, sodium sulfide and ammonia. Diagnostic and operative techniques applicable to acute injury are described.

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In the light of data informed by this study and clinical experiences of the authors and others, it was found logical, in radiotherapy of NPC, that large opposing lateral pre-auriculo-cervical portals with their posterior margin extending beyond the external auditory meatus posteriorly be used in order to avoid geographic miss of the uppermost deep cervical lymph nodes usually involved beneath the jugular foramen and posterior portion of the nasopharynx. Actinomycin D had no effect on 15d-PGJ2-mediated inhibition of IL-10 signalling, indicating that inhibition of IL-10 signalling occurs independently of de novo gene expression. A resampling method is used to control the family-wise error rate to adjust for multiple comparisons.

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On a dark-field signal generated by micrometer-sized calcifications in phase-contrast mammography. Development of a hamster superovulation program and adverse effects of gonadotropins on microfilament formation during oocyte development.

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In AdV and FluA and B infections, fever lasted longer than in other viruses. Prevalence data from different geographical regions have been supplemented by more detailed incidence data on primary antibody deficiencies, revealing trends in diagnosis and management. Because canalicular tight junction permeability can be compromised in damaged livers, both normal rats and rats recovering from the hepatotoxin D-galactosamine were studied. However, experiments, for example, on red blood cells and on lysosome membranes, show that the permeability depends strongly on the choice of salt anion in a way that cannot be accommodated by differences in ionic size. The gapless, midline travel of the Parker tube leads to a greater incidence of first-attempt intubation success with tube-guiding devices, because there is less risk of tube tip hang-ups on the arytenoids and the vocal cords.

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Activation of CDKs generally involves phosphorylation of a loop at a threonine residue. The cloned mouse beta maj-globin gene or the cloned human beta-globin gene was introduced into mice deficient in beta-globin synthesis because of a deletion of the beta maj-globin gene. Negative regulation by amphiphiles was nearly abolished in alpha1V256S-mutated receptors, but potentiation was unaffected.

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Effect of a 21-aminosteroid oxygen free radical scavenger on neurological outcome following complete cerebral ischemia in dogs. Three modes of immunotherapy in the treatment of allergic rhinitis to grass pollen were compared in grass sensitive patients: aqueous extracts, alum precipitated extracts and alum adsorbed extracts from aqueous pyridine solution of grass pollens (Alavac G.). Toward a social theory of sexual risk behavior among men in the Armed Services: understanding the military occupational habitus.

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Genetic diversity and assignment tests among seven French cattle breeds based on microsatellite DNA analysis. The chest wall was compressible, so the protrusion was corrected by means of intrathoracic compression. In this chapter the current knowledge on bacteria-sponge associations is briefly reviewed. In addition, two of the programs search up to 150 residues downstream of tRNA gene sequences for possible eukaryotic RNA polymerase III termination sites comprised of at least four consecutive T residues.

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In HLA-A2-expressing patients, naturally elicited NY-ESO-1-specific, tumor-reactive cytotoxic T lymphocytes (CTLs) are mostly directed against an immunodominant epitope corresponding to peptide NY-ESO-1 157-165. However, it constitutes a diagnostic challenge when it presents in patients with no renal antecedents. A new fermentation process for ethanol production from Thoroughbred, a winter barley variety with a high starch content, was developed. Effects of allogeneic blood transfusion in patients with stage II colon cancer.

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Understanding the mechanisms connecting platelets to tissue regeneration, however, will inevitably open novel options in regenerative medicine. The receptor-binding domain (RBD) on spike protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is the main region interacting with the viral receptor-ACE2 and is a useful target for induction of neutralizing antibodies against SARS-CoV infection.

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VEGF-induced ROS generation from NAD(P)H oxidases protects human leukemic cells from apoptosis. The results provide the basis for the development of long acting, PEGylated GIP, GIP variants, or GIP-based hybrid peptide therapeutics. Bipolar affective disorder is a familial illness characterized by recurrent episodes of mania and depression, but little is known about the familial nature of episode recurrence or its associated clinical features.

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Mnt adenovirus also inhibited platelet-derived growth factor-induced VSMC proliferation. Due to advances in radiation delivery technologies, it is now possible to deliver ablative doses to spinal metastases safely and effectively, and in particular high-dose re-irradiation. The structure of highly concentrated aqueous lithium chloride solutions was investigated by the Reverse Monte Carlo method. Structural properties of biodegradable polyesters and rheological behaviour of their dispersions and films.

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Risk factors for night sweats and hot flushes in midlife: results from a prospective cohort study. There were three conditions, a condition in which the word and nonwords were presented in lower case letters, a condition in which the letters to the left of the central fixation were case alternated (e.g., aMbItion, mOdLants) and a condition in which the letters to the right of fixation were case alternated (e.g., collApSe, pireNtOl). The resulting lower MPO release in the injured tissue is likely to decrease the extent of secondary injury and might at least partially explain the neuroprotective effect of the flavonoid quercetin. Effects of a 12-wk whole-body vibration based intervention to improve type 2 diabetes. Thymectomy and viral infection in humans: evidence for the role of the thymus in adulthood

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Prevention of antibody-mediated rejections in standard-risk and sensitized recipients, as well as newly introduced immunosuppressive substances are covered. Screws and hooks were loaded either axially strictly longitudinal to failure or in a coronal plane strictly perpendicular to the longitudinal axis nondestructively. Mechanical strain alters gene expression in an in vitro model of hypertrophic scarring. The color intensity of adduct was found to increase proportionally with the increase of the substrate concentrations after 5min exposure. Maturity- and sex-related changes in tibial bone geometry, strength and bone-muscle strength indices during growth: a 20-month pQCT study.

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All these cases were randomly controlled and observed for two years. However, all babies with isolated hip clicks eventually had normal hips on clinical and radiographic examination. Predictive value of apoptosis, proliferation, HER-2, and topoisomerase IIalpha for anthracycline chemotherapy in locally advanced breast cancer. To the best of our knowledge this is the first case report delineating the spine pathology via reformatted CT scan and the correction of a windswept deformity by means of temporary hemiepiphysiodesis in a patient with (DSC). Dynamic cyclotorsions have been measured on 10 emmetropic subjects during a simulated PRK treatment.

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A REVIEW OF THE ARGONNE NATIONAL LABORATORY RADIATION EXPOSURE EXPERIENCE FOR THE YEARS 1959-1961. pacerone 200 mg tablets In this study, we demonstrated that Nef from HIV-1 binds to the regulatory subunit (p85) of phosphatidylinositol-3-kinase (PI3K). We also outline how these approaches can inform the development of safer immunomodulatory biologics. We show that this novel domain of approximately 65 amino acids is found in CRF proteins from all groups of land plants and only in CRF genes.

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