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Pidocar (Clopidogrel)
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Clopidogrel

Pidocar bisulfate (Pidocar) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Pidocar prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class of drugs called P2Y12 inhibitors. Other drugs in this class include ticagrelor (Brilinta) and prasugrel (Effient). Pidocar is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, Pidocar bisulfate does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack, and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking.) Pidocar bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Pidocar bisulfate was approved by the FDA in 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Pidocar is used alone or together with aspirin to lessen the chance of a heart attack or stroke. It is given to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with other circulation problems that could cause a stroke or heart attack.

A heart attack or stroke may occur when a blood vessel is blocked by a blood clot. Pidocar is a platelet inhibitor. It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood. Pidocar may also increase the chance of serious bleeding in some people.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Since November 1996, we have treated primary trigeminal neuralgia using the Leksell Gamma Knife at the Tianjin Medical University. Attention is given to the transport behavior of Fe oxides in laboratory systems and in the environment, because of the high affinity of different contaminants to Fe oxide surfaces and associated co-transport of pollutants. The synthesis and analytical properties of 1,3-cyclohexanedione bisthiosemicarbazone monohydrochloride are described for the first time. Thirty sheep which had exhibited clinical signs for more than 15 months were examined for the presence of muscle atrophy, limb paresis, and spontaneous rotational behaviour. The homogeneous discrimination of free components and particle-based assemblies can be extended into the micromolar concentration range.

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In the presence of glutamate receptor blockers, a conditioning pulse delivered to one site of the dentate gyrus inhibits the population synaptic response and the afferent volley provoked by the activation of a second site, in a bicuculline-sensitive manner. Ex vivo activated immune cells promote survival and stimulate multilineage hematopoietic recovery in myelosuppressed mice.

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MEN2A and MEN2B are caused by activating mutations in the RET proto-oncogene, which encodes a tyrosine kinase receptor essential for signal transduction in neural crest-derived tissues, including the peripheral and enteric nervous systems, C cells of the thyroid gland, and chromaffin cells of the adrenal gland. Endemic malignant mesothelioma: exposure to erionite is more important than genetic factors. The wide range of host species in which generalists are able to develop may impede effective host manipulation and could have resulted in regaining of lipogenic ability in generalist parasitoids. Mothers of children with spastic-type CP were included into group 1. Ureteroscopic surgery for a large upper ureteral stone in an infant with bilateral vesicoureteral reflux.

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Reduced training time combined with no rigorous assessment for technical skills makes it difficult for trainees to monitor their competence. Key differences in the presentation, management, and outcomes of severe malaria by endemicity and by age group are emphasized. In this article, the authors examine a number of recently published or presented studies of the atypical antipsychotics, many of them post approval studies, that shed additional light on this class of medications. Another, crisis therapy, stresses brief intervention aimed at rapidly reestablishing previous levels of function, with relatively little concern for insight into developmental causes.

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Responses of Listeria monocytogenes to acid stress and glucose availability monitored by measurements of intracellular pH and viable counts. How well do mean field theories of spiking quadratic-integrate-and-fire networks work in realistic parameter regimes? Proper seated posture is important in health care settings because immobilized patients may be sitting for extended periods. Nerve tissue culture method of studying myelinotoxic antibodies in experimental allergic polyneuritis The technique of SSR amplification is a prerequisite to generate the molecular profiles of various alleles of an individual or genotype.

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Transient receptor potential A1 (TRPA1) is implicated in somatosensory processing and pathological pain sensation. Noncircadian candidate slave oscillators, termed FRQ-less oscillators (FLOs), have been described, each of which appears to regulate aspects of Neurospora growth or development. The general concept of those tests is to mimic in vitro the contact between allergens and circulating basophils.

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The overall incidence was 6.4 percent for 73 boys and 83 girls combined, results that differ from reports of other ethnic groups. Tendon collagen fibrils, fibril bundles, and macroaggregates are intimately associated with these extracytoplasmic domains. The effects of OCs were generally larger in healthy women than in those with MDD. Knee flexion was lower in the static spacer group at 3, 6 and 12 months postoperatively. The few studies analyzing the factors affecting the ROM are scarce.

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It has been surmised that oxygen tension could regulate the cytotrophoblast ability to differentiate and, as a consequence, to express proteins that are critical for placentation. Hemoglobin is a routine examination and anemia is therefore simple and quick to determine.

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Abnormalities in the temporal and extratemporal white matter of patients with temporal-lobe epilepsy (TLE) and mesial temporal sclerosis (MTS) have previously been identified. Recovery time was from scan completion until discharge from the initial recovery area. Technical improvement led to merging in technologies making autofluorescence or narrow band imaging incorporated into one bronchoscope.

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Intravesical treatment with rAd-IFN facilitates high levels of IFN transgene exposure and may be a new approach to treating superficial bladder cancer. This segmentation presumably reflects a neuronal process of temporal integration (TI) which automatically binds successive events into temporal units. Although PD patients demonstrated a reduced ability to convey contrastive stress, they could still notably increase pitch, intensity, and duration to emphasize a word within a sentence. IODINE-131 IN FRESH MILK AND HUMAN THYROIDS FOLLOWING A SINGLE DEPOSITION OF NUCLEAR TEST FALLOUT. Retinas from two human fetuses at approximately four months of gestation were also examined for their histone content.

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Neuropsychiatric changes following surgery for chronic subdural hematomas (CSDHs) were analyzed in 26 patients (21 men and five women) by using the Mini-Mental State Examination (MMSE) and the Hasegawa Dementia Scale-Revised (HDS-R) to determine factors that potentially contribute to neuropsychiatric recovery. In this article, I summarize our current knowledge regarding anti-IL-5 therapy and speculate on the potential use of these drugs in the future.

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Critical study of the effect of prolonged hyperbaric oxygen with intermittent sessions on the course of severe neurologic lesions Parity and risk of colorectal cancer: a dose-response meta-analysis of prospective studies.

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This will be analysed within the context of genetic screening and testing, as well as codes of practice and guidelines. Scalable nano-particle assembly by efficient light-induced concentration and fusion. Lack of independent movement of an adjacent mass and ovary was strongly associated with absence of ectopic pregnancy.

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The mild indirect hyperbilirubinemia associated with impairment in conjugation tends to be well tolerated and of little consequence. Sperm and testes-expressed Adam genes have been shown to undergo bouts of positive selection in mammals. Assessment of left ventricular (LV) rotation has become an important approach for quantifying LV function.

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Forced orthodontic extrusion is strongly related to interactions of teeth with their supportive periodontal tissues. These findings suggest that s-drebrin A has a role in spine morphogenesis, possibly by competing the actin-binding activity with drebrin A. Patients underwent pure tone audiometry at baseline (before treatment) and 1, 6, 12, 24, and 36 months after RT. We will also discuss the potential effect of ultrasound on systemic thrombolysis.

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KX-01 alone and in combination with oxaliplatin significantly inhibited tumor growth by reducing cell proliferation and inducing apoptosis in vivo. Determination of lead and nickel in Apple-Leaves and sea-water by electrothermal atomic absorption spectrometry after solid-phase extraction using Chromosorb-107 filled in a syringe. Thus, our data suggest that the sucrose-induced hypocotyl elongation in the dark does not result from GA-induced degradation of DELLAs. Torsion of the gallbladder is an unusual cause of gangrenous cholecystitis.

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Multiple novel agents directed towards different molecular targets like BTK, mTOR, PI3K, HDAC, and BCL-2, involved in the pathogenesis of MCL have shown promising results. An overview of recent developments in the Trp analog incorporation field is also presented. Like other membrane-interacting agents (polar solvents), all the polymers tested were effective in inducing cell differentiation.

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Detection of endoleak with enhanced ultrasound imaging: comparison with biphasic computed tomography. In this study, drug compliance was satisfactory in almost three-fourths of the patients with epilepsy.

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We compared these distributions with those of the glucose transporter 1 (GLUT1/Slc2a1). Measurement of NMHb in blood is recommended rather than measurement of NMF and AMCC in urine to accurately assess exposure to DMF in health risk assessment. Furthermore, some key issues that need to be addressed for future discovery of novel antidepressant agents are examined, and the available data on genetically altered mice that might lead to the discovery of novel targets for antidepressant action are collated. Ketorolac can be given safely in children with minimal risk and when combined with caudal analgesia it facilitates early discharge home. DGGE analysis performed after PCR with Archaea- and Crenarchaeota-specific primers showed that archaea related to uncultured environmental clones, particularly those of the Crenarchaeota phylum, were present in both carbohydrate- and protein-degrading communities.

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The mechanisms of blood vessel closure in humans by the application of ultrasonic energy. These data are consistent with the hypothesis that testicular and adrenal 3 beta HSD is encoded by the same structural gene but that expression of 3 beta HSD activity is independently controlled in testes and adrenal glands. Here we provide evidence that ANGPTL4 is a blood-borne hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. A computational model for maximal expiratory flow in constricted lungs is presented.

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Development of ART has great benefit for millions of couples all over the world and with falling fertility rate there are a growing numbers of children born with the help of ART, it is important to investigate potential risks to these children. Complete glycosylphosphatidylinositol anchors are required in Candida albicans for full morphogenesis, virulence and resistance to macrophages. Postoperative coronary angiography was performed in 40 patients with suspected myocardial ischemia. Urinary diversion in cases of ureteral injury during gynecologic operations

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Duodenal, jejunal and ileal segments displayed differences in microvillous amplification factors, absolute surface areas and mean lengths but no significant differences in the mean diameters or packing densities of microvilli. Aberrant expression of embryonic epithelial-mesenchymal transition-inducing transcription factors (EMT-TFs) in epithelial cells triggers EMT, neoplastic transformation, stemness, and metastatic dissemination. Slc26a6 activity was assayed by measuring intracellular pH, and CFTR activity was assayed by measuring Cl(-) current. Breakup of a transient wetting layer in polymer blend thin films: unification with 1D phase equilibria.

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Preliminary studies have suggested that such procedures are adequately efficacious. Dynamic continuous-flow dialysis method to simulate intestinal digestion for in vitro estimation of mineral bioavailability of food. Patches of CVX and PDX had heaping mucosa at the margin of well-sealed patch edges in the study involving duodenum. Twenty-seven aerobes and 41 anaerobes were found in isolates from patients with chronic sinusitis.

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Indirect evidence from populations without PCOS demonstrated no increased risk of lactic acidosis with metformin, only case reports of liver toxicity with flutamide (no comparative evidence), and increased relative risk difference of venous thromboembolism with oral contraceptive pills but very low absolute risk. This diagnosis was taken on the basis of general symptoms, skin lesions, hemolytic anemia, thrombocytopenia and glomerulonephritis (class III).

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The results of the study suggest that DDC mRNA expression may be regarded as a novel potential tissue biomarker in colorectal adenocarcinoma. In this review we will examine receptor signaling pathways initiated from five receptors that are all involved in either initiating T helper-1 (Th1) responses, or in downregulating Th1 responses. Concussion management and treatment considerations in the adolescent population.

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In this study, we used the SM22 gene as a model to address whether transcriptional activation of the gene can be manipulated through adjusting histone acetylation of the chromatin template and whether SRF- and HAT-containing coactivators can be recruited onto the SM22 promoter region during gene activation. A total of 32 randomized, non-invasive blood pressure series, each consisting of three measurements from each monitor, were obtained from 20 neonates (birthweight 531-4660 g). As well as being phytohormones, gibberellins (GAs) are present in some fungi and bacteria.

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Theoretical analysis indicates that the proposed method reconstructs the oracle estimator, that is, the unbiased least squares estimator given the true grouping, leading to consistent reconstruction of grouping structures and informative features, as well as to optimal parameter estimation. Calcitonin for the long-term prevention and treatment of postmenopausal osteoporosis. Mortality reduction in HCV infected individuals will require comprehensive prevention programming to reduce the harms due to behaviours/activities which relate to HCV acquisition, as well as HCV treatment to prevent progression of chronic liver disease.

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As atherosclerotic cardiovascular diseases are rooted in childhood, our findings suggest that special attention could be paid to children who are from low socioeconomic status families, and who smoke or whose parents smoke, to prevent cardiovascular disease morbidity and mortality. However, whether this role of DNA methylation is important in the context of transcriptional regulation is unclear. However, care will be required in performing and interpreting these association studies. Alteration of the circadian rhythm and increased vascular senescence are linked to cardiovascular disease. Genetic determinants of drug-induced cholestasis and intrahepatic cholestasis of pregnancy.

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Our procedure provides optimal source selection results independent of the user experience and in a short amount of time. In the group of young participants, novel stimuli replacing the first member of the letter pair elicited a long-lasting anterior negative ERP component. A recently proposed analytical technique to determine whether an inotropic agent improves cardiac pumping performance via its vasodilatory or its positive inotropic effects was adopted to evaluate the pharmacological properties of a positive inotropic agent, dobutamine, and a vasodilatory calcium antagonist, felodipine, in patients with severe heart failure. young rats was accompanied by greater damage of cortical tissue and persistent elevations in corticosterone levels.

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Combinatorial protein libraries offer a solution to the generation of collections of specific binders, but unit operations in the process to isolate binders from such libraries must be automatable to ensure an efficient procedure. 1,085 patients listed for LT during the time period 2004-2011 were included in our analysis.

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A series of 16 patients underwent surgical resection of spheno-orbital meningiomas followed by bony reconstruction. After an additional month, 8-mm long hydroxyapatite-coated titanium implants were placed in such a way that the apical half was embedded into alveolar bone and the coronal half in the preformed CPC block. GH treatment was associated with a marked increase in thymic mass in all GH recipients.

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This setup is known as in-line or propagation based phase contrast imaging. Biopsy specimens (4 mm) from donor wounds were evaluated for percentage neoepidermal coverage in tissue sections immunostained for keratin on days 5 and 8. Role of molecular subtype in predicting outcome of AIDS-related diffuse large B-cell lymphoma. This double-blind, placebo-controlled phase II study examined the safety, tolerability, and dose of repinotan in patients with acute ischemic stroke. The valuation of malnutrition in the mono-digestion of maize silage by anaerobic batch tests.

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Subjects with AP had significantly elevated proportions of spirochetes and motile rods and lower proportions of coccoid cells than H subjects. Bridging the synaptic gap: neuroligins and neurexin I in Apis mellifera.

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Novel prostanoids, including subcutaneous treprostinil and inhaled iloprost, also have beneficial effects in many patients, although their long-term efficacy is less well known. The patients were studied using clinical and neurophysiological methods, electroneuromyography and somatosensory evoked potentials (SSEP).

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The chemical structure was determined to be 5-beta-d-xylofuranosylneamine, which is identical to the deacylated product obtained from butirosin A. schite cotet iepuri cap Exploratory analysis of longitudinal trials with staggered intervention times. Also, exposure to the oligomers arrested the cells at the G(0)/G(1 )phase and inhibited cell migration. We suggest that malaria vector control measures aimed at adult mosquitoes might be made more efficient in this region and other seasonal riparian habitats by targeting disruption of mosquito populations by the river during the dry season.

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Metabolic side effects of augmentin syrup and chemical heterogeneity in calf rib cartilage as revealed by CsCl gradient centrifugation and CPC-cellulose chromatography. Gene regulatory patterns combined with phylogenetic inferences of the hsp70 gene support a possible role of ecologically driven divergence within the genus Aurelia.

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As the h.pylori treatment with levofloxacin research demonstrated only slight variation in the spawning period between sites, despite site differences in water and environmental quality, temperature and variable climatic conditions were the dominant factor controlling gametogenesis. However, periodontal diseases in HIV-seropositive and HIV-seronegative subjects are similar with regard to the spectrum of periodontopathic bacteria, clinical manifestation, natural course of the disease and response to treatment.

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NKT cells, a novel murine lymphoid lineage bearing an invariant T cell receptor encoded by V alpha 14 and J alpha 281 gene segments, recognize a specific ligand glycolipid, alpha-galactosylceramide (alpha-GalCer) in a CD1d-dependent manner. Endothelial cell-specific solid self-microemulsifying drug delivery system of ritonavir over-expression of endothelin-1 leads to more severe cerebral damage following transient middle cerebral artery occlusion.

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A logistic regression analysis was norfloxacin eye drops cipla share performed to assess the odds ratios of HGPIN for the presence of PCa in 22 regions. 1999, 64, 6023-6031), it is found that 2 reacts rapidly with a variety of nucleophiles. Failure of Internet-based audit and feedback to improve quality of care delivered by primary care residents. The findings add to the evidence for the importance of maternal warmth and contextual risk for both regulated emotion and regulated behaviour.

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In adults, pheromone exposure increased the number of Fos-positive neurons in the main olfactory bulb without changes in the accessory olfactory bulb. The balance between acetylation and deacetylation controls Smad7 stability. Noninvasive evaluation of the celiac kegunaan ubat zolterol medicine trunk and superior mesenteric artery with multislice CT in patients with chronic mesenteric ischaemia. The authors have termed this structure the limbal epithelial crypt. The LCO protocol enables high-resolution imaging of several different protein aggregates, such as Abeta1-42, Abeta1-42(E22G), Transthyretin V30M and human Tau, in the Drosophila brain.

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Replicative senescence limits cellular proliferation in vivo and in vitro. The relationships between neuroimaging and neurocognitive abnormalities in BPD are worthy of additional investigation. These studies have shown a decreased susceptibility to develop lung carcinomas induced lorazepam and alcohol high cholesterol by chemical carcinogens in Mmp1a(-/-) mice.

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For the distal IPA or cavernosal arteries, MDCT showed a high sensitivity and low specificity. The purpose of this study was to characterize disease burden by evaluating readmissions, mortality, and medical cost during the levofloxacin ornidazole dosage first year after acute stroke under the National Health Insurance (NHI) program. This paper reports an analysis of the principles underlying human performances on the basis of the work initiated by Pietro Enrico di Prampero. While combination chemotherapy or biochemotherapy may be considered in certain circumstances, it is now clear that single-agent chemotherapy remains the mainstay of treatment for the majority of patients.A number of new agents and novel approaches are under evaluation and show promise. Prediction of constitutive A-to-I editing sites from human transcriptomes in the absence of genomic sequences.