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Saphire (Atorvastatin)

Saphire versus micronized fenofibrate in the treatment of patients with mixed hyperlipoproteinemia. Association of genetic variations with pharmacokinetics and lipid-lowering response to Saphire in healthy Korean subjects. All doses of Saphire were generally well tolerated, with similar incidences of adverse events across all dose groups and placebo.

Other names for this medication:
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Saphire is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (e.g., chest pain, heart attack, or stroke) that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel problems in patients with risk factors for heart problems.

Saphire belongs to the group of medicines called HMG-CoA reductase inhibitors, or statins. It works by blocking an enzyme that is needed by the body to make cholesterol, and this reduces the amount of cholesterol in the blood.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Equilibrium reactions network for the cis- or trans-bis(pyrazine)tetraammineruthenium(II/III) and ruthenium(II/III)-EDTA complexes. THE ISOLATION OF COAGULASE-POSITIVE ENTEROCOCCI FROM CLINICAL MATERIAL. However, in Drosophila melanogaster SL2 cells, only p107 was able to repress Sp1-mediated transactivation of the FGFR1 promoter.

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Membrane permeability and potential was studied using LIVE/DEAD viability assay and using Bis (1, 3-dibutylbarbituric acid) trimethine oxonol (DiBAC4), respectively. In the direction parallel to the force, mean-square displacements show anomalous superdiffusion in the long time limit. AA and ANA pups were assigned to one of three different rearing conditions: 15 min (MS15) or 360 min (MS360) of daily maternal separation in litters or normal animal facility rearing (AFR) during postnatal days 1 to 21.

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This review summarizes human epidemiology data linking silica exposure with systemic autoimmune disease, but focuses on possible mechanisms by which silica can lead to the development and progression of autoimmunity. The highest adhesive values between buildup and ceramic were obtained using the materials Compoglass F and Syntac, followed by Compoglass F and ExciTE. Removal or drastic reduction of external sodium caused a hyperpolarization of the BTX-poisoned membrane.

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A proteomic-based approach for detection of chicken in meat mixes. Microbial enzymes are preferred due to their economic feasibility, high yields, consistency, ease of product modification and optimization, regular supply due to absence of seasonal fluctuations, rapid growth of microbes on inexpensive media, stability, and greater catalytic activity.

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gingivalis LPS-induced expression of MMP-3 were examined by blocking assays. The analytical method was applied to determine ethyl xanthate in a sulphide mineral flotation plant and the amount of adsorbed ethyl xanthate and diethyl dithiophosphate on Cu(2)S.

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Do individuals with a family history of colorectal cancer adhere to medical recommendations for the prevention of colorectal cancer? To investigate whether participation in a clinical audit and education session would improve GP management of patients who smoke. Here, we combine eight human population-genetic data sets at the 645 microsatellite loci they share in common, accounting for procedural differences in the production of the different data sets, to assemble a single data set containing 5795 individuals from 267 worldwide populations. Implantation requires angiography and a minor surgical procedure. We report a case of a giant ovarian cystic tumor with possible DVT.

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Protein S-nitrosylation, the posttranslational modification of cysteine thiols to form S-nitrosothiols, is a principle mechanism of nitric oxide-based signaling. To determine the structural basis for 2B4/CD48 interaction, selected amino acid residues in the V domain of the human 2B4 (h2B4) were mutated to alanine by site-directed mutagenesis. Systematic review of the psychometric properties of the questionnaire to evaluate the adherence to HIV therapy (CEAT-VIH). Synthesis and inclusion behavior of cyclotriphosphazene molecules with asymmetric spiro rings. Prnp gene and cerebellum volume in patients with refractory mesial temporal lobe epilepsy.

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The enzyme was very stable at pH 4.0-6.0 with an optimum pH 5.0 at 40 degrees C. Arthroscopic findings of the hip in new onset hip pain in adolescents with previous Legg-Calve-Perthes disease. To define the clinicopathological features and discuss the optimal management of carcinoma showing thymus-like differentiation (CASTLE). Surgical techniques have recently been introduced for patients with vitiligo. Candidaemia in an Irish tertiary referral hospital: epidemiology and prognostic factors.

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The patient was later diagnosed with Guillain-Barre syndrome with Henoch-Schonlein purpura. To develop an immunodelusive immunoisolated bioartificial pancreas (BAP), chondrocyte sheets were prepared by cell sheet engineering. Proton pump inhibitors are the first-line therapy as some eosinophilic oesophagitis phenotypes respond well to proton pump inhibitors.

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However, an additional unique feature of these acridan-based reagents is the generation of a fluorescent species on reaction with peroxidase, a property which has been termed as chemifluorescence. We have constructed an automated Fe(II), total dissolved iron(TDI), Mn(II), and total dissolved manganese(TDM) analysis system for the quality control of underground drinking water by reverse flow injection analysis and chemiluminescence detection(rFIA-CL). Early and late effects of fractionated irradiation of the thorax of WAG/Rij rats. In electron impact gas chromatography (GC)-mass spectrometry analysis of a complex mixture, such as gasoline, two coeluting solutes can be distinguished if each has a unique major ion.

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Children with isolated hemihypertrophy are at increased risk for neoplasms. Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting both upper and lower motor neurons.

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A majority of underage students supported increasing efforts to control underage drinking. By quantitative RT-PCR the sst subtype expression level was determined in human corticotroph adenomas. salmonicida that were studied required arginine and lysine, among other amino acids, for their growth. Body mass index was positively associated with systolic blood pressure in both groups. Adding confidence as a second dimension slightly improved the ability to predict readiness.

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Embryonic exposure of medaka (Oryzias latipes) to propylparaben: effects on early development and post-hatching growth. Early detection of complications after gastrostomy: summary of a safety report from the National Patient Safety Agency.

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In addition, used PDMS stamps were analyzed with scanning electron microscopy (SEM) to observe topographical changes that occur during oxygen plasma-treatment. Developing Research Domain Criteria (RDoC) to improve diagnosis and treatment of social deficits in psychiatric disorders: the Mirror Neuron System as a model. The population of grid cells drives the activity of place cells coding individual locations.

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Finally, we showed that ONs with flanking LNAs aimed at correcting the rd1 stop mutation could promote survival of photoreceptors in retinas of rd1 mutant mice, suggesting that they are also active in vivo. Statin treatment may reduce the incidence of major adverse cardiac events in subjects with the metabolic syndrome, but evidence is limited. Prospective data analysis with documentation of initial injury and treatment strategy, computed tomography scans, conventional x-rays, long-term evaluation of radiographs, and functional assessments. However, the dynamics of wild host-parasite systems exposed to a reservoir of domesticated hosts are not well understood.

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A particularly thorough hematological evaluation should be conducted upon entrance to the work force at risk. The current results are consistent with our previous report of PKCgamma in hippocampal homogenates, and show further that the relationships between PKCgamma-ir and memory impairments among aged rats are most evident in area CA1. DNA methylation plays a central role in the control of gene expression during development and cell differentiation, thus DNA methylation and demethylation processes are expected to be strictly regulated during these events. Plurality of principal angles for a given pseudo-Brewster angle when polarized light is reflected at a dielectric-conductor interface.

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In the high risk cohort predictors of the type of primary treatment, and the use of neoadjuvant and adjuvant androgen therapy were identified. In no case was there evidence of in vivo lymphocytosis or blastogenesis.

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It seems to us that this treatment is most effectively carried out in hospital, where it is possible to achieve constant heparinization by electric syringe and reequilibration of the biological constants. Furthermore, poloxamers F68 and F127, and PVA stabilizers demonstrated the best performance in increasing dissolution efficacy.

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In Phase II, meniscus cell-seeded PLLA constructs were cultured for 4 wks with a combination of TGF-beta1 and HP (10 MPa, 0 Hz or 10 MPa, 0.1 Hz). GABA(A) Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels. Cognitive-behavioral treatment of bulimia nervosa: a controlled evaluation.

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In contrast, hyperalgesia induced by a specific PKCepsilon agonist depended only on alpha5 and beta1 integrins. The significantly higher motor response amplitudes and decreased latency in the late postoperative stage for the laparoscopic group may be due to the fact that this technique is less invasive. Two tyrosines are required for Reelin to stimulate Dab1 phosphorylation at the other sites, to activate Akt, and to downregulate Dab1 levels. mre11(-/-) null mutant strains exhibited retarded growth but no delay or disruption of cell cycle progression.

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Cases with similar features are reviewed and genetic mutations discussed. As a result, a huge amount of cations can be solubilized, thus inducing groundwater pollution. This X-ray detector is used in a Full Field-of-view Digital Mammography (FFDM) camera. Mechanical circulatory support for bridge to decision: which device and when to decide.

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The effect of the field strength on standardized MRI of the brain to demonstrate cranial nerves and vessels: a comparison of 1.5 and 3.0 Tesla Therefore, arsenic metabolites in the body fluids and organs/tissues are present in the form of inorganic (arsenite and arsenate) and methylated arsenics (MMA and DMA).

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rhinoscleromatis infections induced a classical inflammatory reaction, K. All five patients possessed HLA-B51 or HLA-B52, and all had fever and an enhanced inflammatory response at the time of the WBC nadir.

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The tumor was treated by wedge resection and, in the frozen section examination, there were pancreatic ducts in the proper muscle layer, pancreatic acini with islets of Langerhans under the serosal surface and mucinous lakes close to the heterotopic pancreatic tissue and to a peripheral nerve. A relationship exists between the type of substitution on the 12-crown-4 and the complexing ability and selectivity. The latter type of coordination was found by developing a purely spatial analysis that yielded measures of similarity between images, eye trajectories, and pen trajectories. Lactose, fructose, and sorbitol should not be used as substrates in the assessment of suspected SIBO.

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Takeoffs are characterized by higher hindlimb than forelimb peak forces and impulses. We test whether advanced real-time rendering techniques combined with an effective user interface will allow radiologists and surgeons to improve their performance for cardiothoracic surgery planning and diagnostic evaluation. The study revealed that the drug acts mostly on the late S and G2 phase of the cell cycle. The WHR is predictive of adverse events after elective colorectal surgery.

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The preventive effect of amrinone on ischaemia/reperfusion (I/R) injury has been shown in the medical literature. Delirium is a highly prevalent disorder among older patients in intensive care units (ICUs). Here, we describe how eudicot plants recruited conserved shoot meristematic factors to regulate growth of the basic simple leaf blade and how subsets of these factors are subsequently re-employed to promote and maintain further organogenic potential. CD25 saturation rate in heart transplant patients receiving two-dose daclizumab induction.

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DeltaNp63alpha repression of the Notch1 gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells. This article is part of a theme issue of Academic Medicine on the Title VII health professions training programs. We performed the present experiment using dogs to study the effects and safety of LVRS using the SST.

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Therefore, we investigated the regulation of HGF by steroid hormones in isolated macrophages and stromal cells derived from women with or without endometriosis. Namely, all previously known miRNAs in other plant species were blasted against lettuce EST sequences to select novel miRNAs in lettuce by a series of filtering criteria.

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Bloodstream infections caused by Gram-negative bacilli are a substantial cause of morbidity and mortality in infants in neonatal intensive care units. Hydrometallurgical recovery of zinc from ashes of automobile tire wastes. Given the central roles played by lipoproteins and inflammation in atherogenesis, effective anti-atherosclerotic treatments should both modify the lipid profile and target the ongoing inflammation.

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Here we show that global representations, on the basis of parameters that encode information about complete sequences, contain otherwise inaccessible information about the organization of sequences. Multiband multislice GE-EPI at 7 tesla, with 16-fold acceleration using partial parallel imaging with application to high spatial and temporal whole-brain fMRI. There is an increased interest in utilizing mechanistic data in support of the cancer risk assessment process for ionizing radiation and environmental chemical exposures. With the availability of antiretroviral drugs in resource-limited settings, there is a rapid scale-up of antiretroviral therapy in developing countries. Using a combination of radioassays and Fourier transform mass spectrometry, we demonstrate that once FkbP has been phosphopantetheinylated in vitro, its peptidyl carrier protein domain can be successfully loaded with l-pipecolic acid and, to a lesser extent, l-proline.

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Analyses of the simulations reveal that a single residue differentiates between two different and otherwise conserved dynamic processes in a region of the protein known to form part of the substrate-binding interface. Hypopharyngeal lipoma causing obstructive sleep apnea: Discovery on dental cone-beam CT.

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Predictive factors for psychiatric morbidity among women with infertility attending a gynaecology clinic in Nigeria. We performed a multicenter (6 centers in Spain), case-control study to assess PBM using dual-energy x-ray absorptiometry. Obtaining the EEG envelope in real time: a practical method based on homomorphic filtering.

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Subsequent UBE2A screening of a phenotypically similar second family revealed another missense mutation, R11Q, again affecting an evolutionarily conserved amino acid close to the N-terminus of the protein. Ultrasonic determination of fetal maturity at repeat cesarean section. The recycling of carbon in glucose, lactate and alanine in sheep. The U6 promoter cassette and siFas (small interfering RNA that inhibit Fas expression) template sequence were obtained by PCR method.

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Hepcidin may play a role in the pathogenesis of anemia, but its role in kidney transplantation is undefined. The mock oral examination, which is conducted in a conference format in front of an audience of faculty and trainees, is a valuable educational tool as it helps both the examinee and the audience in preparation for the ABS CE. Finally, the conclusion is that a too radical change of the classificatory system, e.g. During the last decades, therefore, nonlinear analysis methods have gained a growing interest to analyze the chaotic nature of cardiac activity.

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Various researchers employed different expression systems and strategies for recombinant NS1 protein production. However, local incentive structures also appear to be important. Warfarin is widely used in patients with non-valvular atrial fibrillation (AF) because it is effective in reducing thromboembolic complications. Should we add oil to complementary foods for breastfed children in developing countries?

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To investigate whether Chinese medicine (CM) syndrome is associated with particular molecular mechanism, we explored the correlation between CM syndrome and changes of intercellular adhesion molecule-1 (ICAM-1), matrix metalloproteinase 9 (MMP-9) and heat shock protein 70 (HSP70) in patients with ischemic stroke, which were reported to play an important role in the inflammatory and apoptosis cascade. Scanning electron microscopical observations of perindopril sandoz 8 mg two novel hemostatic polymers. Weight did not significantly change after aripiprazole administration. To achieve reduction of an acute acromioclavicular (AC) joint separation, novel procedures aim to provide stability and function by restoring the coracoclavicular anatomy.

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PTEN is a major negative regulator of the PI3K/Akt signaling pathway. In the cytoplasm of the manubria there are numerous secretive vesicles filled with fine-granular substance discharged outside plasmalemma, active Golgi apparatus, well-developed excalibur exomax draw weight on a bow rough ER, numerous polysomes, mitochondria with the condensed structure and plastids with granar and inter-granar thylakoids as well as plastoglobules which increase in number and size along with the development of the antheridium. A review committee was formed to prospectively study the patterns of suicide attempts that occurred in the system after the program was implemented and to make recommendations for improvements. Lupus enteritis is the most common cause of acute abdominal pain in SLE. The patient, a 48-year-old woman, presented with severe ventricular arrhythmia and exercise intolerance.

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Block of Stat-1 activation in macrophages phagocytosing bacteria causes reduced transcription of virosol degreaser recipe CIITA and consequent impaired antigen presentation. Low frequency magnetic response in antiferromagnetically coupled Fe/Cr multilayers. Moreover, riding during the night, on weekends, for leisure purposes and along roads in perfect condition, mainly on curves, predict offenses among motorcyclists.

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Characterization of human folylpolyglutamate synthetase expressed in Chinese hamster ovary cells. Some of these biochemical differences may reflect different dietary lifestyle in the Chinese. Three video-cameras captured algorithm time citalopram vs escitalopram qt prolongation arrhythmia data, CPR technique and communication.

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The aim was to investigate the prevalence and incidence of neck/shoulder and back pain in nursing students in their final semester, and one and two years after graduation. During its maturation process, the SCV interacts extensively with host cell endocytic compartments, especially late endosomes/lysosomes (LE/Lys) at later stages. Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies. Two models, the displaced oscillator model and the displaced-distorted oscillator model, based lanex larg meijers store on the harmonic potential energy surfaces are carried out to calculate the surface-enhanced Raman scattering excitation profiles of the pyridine molecule adsorbed on a silver electrode, for which the density functional theory method is applied to evaluate the potential energy surfaces of the adsorption structure.

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Gastric ribavirin drug and gallbladder carcinoma in a patient with multiple myeloma Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography. Partial intestinal obstruction secondary to multiple lipomas within jejunal duplication cyst: a case report.